Research
| Micromanipulation of Particles and
Cells Using Ultrasound |
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"Fluid and particle
manipulation with physical force fields for medical micro-system
applications"
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Glass plate device
Video 1: Positioning of
MCF10A cells in lines
Video 2: Positioning of HeLa cells
at points
Mechanical
gripping of particles aided by acoustic manipulation
Particles (74 um)
randomly distributed in a 1mm wide, 200 um deep micromachined channel are
prepositioned along its centerline by the use of acoustic forces, before being
removed from it for further handling by means of a microgripper, once the
acoustic field has been removed. For better positioning, after a rough alignment
at the center at 780 kHz the frequency has been switched to 2.14 MHz to tighten
the line. After turning the acoustic field on again, particles are repositioned
for the next removal process.
Detailed information:
A. Neild et al, J. Micromech. Microeng. 16 (2006) 1562-1570,
doi:10.1088/0960-1317/16/8/017