Dr.
Daniel Bächi
Research
We
developed a microfabricated system, which uses a new handling method to
manipulate very small particles in fluids (see picture below). Such a mechanical system is ideally suited
for the preparation of samples containing particles, e.g. body fluids, and for
the manipulation of cells or bacteria contained therein. The system has
means for both manipulation and detection of particles with sizes of up to two
micrometers. During the work on the system, models were developed to predict
the system performance. These models showed excellent agreement with the
experimental data.
I
consider clinical diagnostic testing to be the most interesting application for
the developed technology, especially “point of care” testing. The benefit of
having immediate test results at every patient’s bed is obvious. Nowadays, only
a few such tests are available and they are all based on a simple chemistry.
The goal is to perform the more complex processes as in the large centralized
labs of today in a “lab on a chip”. These micro-labs will thus have to work
with bodyfluids, i. e. particles in fluid suspension. The particle handling is
a crucial part of such a system.
Publications
Conferences
Baechi, Buser, Eurosensors
XIII, Den Haag, 1999 (English abstract)
Baechi, Buser,
Dual, Nanoforum CH-US,
Baechi, Buser, IMECE
99,
Baechi, Buser,
Dual, BioMEMS 2000,
Baechi, Buser, Dual, MEMS 2001,
Buser, Buchel, Baechi, Day, Transducers ’01,
Baechi, invited speaker, Biotech 2002, Wädenswil, 2002
Baechi, Bestmann, invited speaker, 1st International Molis
Convention,
Patents
Baechi, Buser, European patent application No. 99810819.5
Baechi, Swiss patent application No. 2001 1544 / 01
Reviewed Journal Papers
Baechi, Buser, Sensors and Actuators, Vol. B63, 2000, p.195-200 (English abstract)
Haefliger, Baechi, Buser, Dual, Microsystems Technologies, Vol. 6
No. 6, 2000, p.229-234 (English abstract)
Baechi, Buser, Dual, Journal of Nanoparticle Research, Vol. 2,
No. 4, 2000, p.393-399 (English abstract)
Baechi, Buser, Dual, Journal of Biomedical Microdevices, Vol. 3
No. 3, 2001, p.183-190 (English abstract)
Baechi, Buser, Dual, Sensors and Actuators, Vol. A95, 2002,
p.77-83 (English abstract)
Thesis
Daniel Baechi, Suspension Handling System, A
Micromachined Channel Network with integrated Actuators and Sensors,
Dissertation No.14178, Eidgenössische Technische Hochschule, Zürich, 2001,
Available from: Shaker Verlag (English and German abstract)
Contact
Mobile +41 79 299 14 88
eMail dbaechi@swissonline.ch
Links
MEMS Group, Institute of Mechanical
Systems, ETH Zurich
Institut für Mikrosystemtechnik, Interstaatliche Fachhochschule für
Technik Buchs
Daniel Bächi 02-Sept-11